You can shoot your reloads. The Handi will handle more than the Marlin, and almost as much as the Ruger. When your shoulder separates, you have reached your max!
Garrett makes "dangerous game" ammo, and the H&R is listed with the Ruger.
This applies to modern H&R's with the SB2 frame, and not the Shikari of course. (See the FAQ's at the top of this forum).
Ben