I have both the 45/70 and 460 in the Katahdin setups, I have taken deer with the 45/70 using both the Hornady bullets and Remington 300 grain hp, just got the 460 over winter so I haven't had a chance to try it out on anything yet but accuracy is really good using the Hornady pistol ammo. The only real swaying point for me would be availability of ammo, where I live in VT the 460 ammo is pretty scarce, but 45/70 is easily available.