Now I am sure that many will argue this point. In the camp where we hunt for Michigan Black Bear, we crack jokes about the number of bear that have gotten away after being struck by 350 mag. Of course shot placement is everything, but there is something about that caliber that doesn't seem to drop them in there tracks like a 7mm mag, or 338. The ballistics don't lie, I know, just consistently poor results on the animals.
Just my opinion!