If that H&R rifle you are talking about is th break-open single shot built on the old Model 158 "Topper" frame, the answer is NO. You can't re-chamber to the .454 Casull because the .450 Marlin chamber is already larger in diameter than the .454 casull, which is same diameter as the .45 Colt.
In addition, the fatter belt of the .450 Marlin chamber would prevent rechambering to .45-70, .458 American, .458 Winchester, etc. because a standard belted cartrige would not headspace properly. The .45-70 chamber would have that fat belt (UGH!) at a critical point near the cartridge head and be unsafe.
Short of being forced to handload more mild .450 Marlin ammunition, I dunno what you can do to make that gun shoot easier....