Henry1,
Load 3.5 to 4 gr of Unique into a 44 mag case, use a wooden dowl to push a gas check tight against the powder, put in shot to almost the top of the case, place a gas check, cup side down, over the shot and crimp with a lee factory crimp die.
This load will kill grouse out to 30 feet and is great to thin starlings in your yard or shoot woodpeckers off the eves of your house. Oh yes, it will kill snakes too.
You can use whatever size shot you want to. I use 7.5 shot.
Sixgun