Like a lot of shooters, the public range where I do most of my shooting only goes as far as 100 yards. And about all the deer I've shot have been within 100 yards. Until going for prairie dogs last year, I'd never shot any further (my "Kentucky windage & elevation" on prairie dogs met with mixed results).
Earlier today I joined a coworker at a gun club he belongs to where you can shoot out to 500 yards. I produced the following group sizes with handloads that consistently shoot under 1" from the bench at 100 yards:
Rem 700VSF in .308 Win: 200 yds, 3 shots - 3.32", 1.60"
335 yds, 3 shots - 1.54", 2.01", 8.32"
400 yds, 3 shots - 6.04"
Savage 12 in .22-250 Rem: 200 yds, 4 shots - 2.43", 1.68", 0.68"
335 yds, 4 shots - 3.40", 4.21"
400 yds, 4 shots - 6.40"
Not too bad considering how windy it was. But as I figured would be the case, shooting under 1" at 100 yds doesn't necessarily translate into less than 4" at 400 yds. Maybe 300-400 yards and beyond is what separates an accurate, factory rifle from a presumably very accurate custom rifle. Could also be at 100 yards, issues such as a heavy trigger, poor bench form or other factors don't make that big a difference, but become magnified at longer yardages.
I now have even more respect for those guys on Best of the West who routinely make one-shot kills at 400-800 yards on their show.