I've just discovered this forum, but I've been shooting cast bullets for 30 years, mostly in handguns and 45-70's.  I've had best accuracy at black powder velocities, whether using smokless, black or duplex loads, with alloys that are fairly soft--about 4ww/1pb or 20-1.  I'm shooting them 1 to 3 thou over groove diameter, so obduration shouldn't be a factor.  this is ture of 45-70, as well as 44 mag at 44 sp velocities in my model 29 and in a browing lowall.  Harder alloys don't shoot as well.
I know we need hard alloys at higher velocities, but is there some converse rule that says we should use softer alloys at slow velocities?