I shoot all handloads. My favorite load for my Encore 30-06, was actually developed for my NEF 30-06. It is a Sierria 165gr Boattail, in front of 49.5gr IMR 4064. I'm shooting a 3 1/4" group at 300 yards. My neighbor's 15 year old son used my Encore and that load, to shoot a nice Bull Caribou yesterday down on the Denali Highway. My rangefinder said it was 278 yards. One shot, caribou down.
The only .380 I own is a Parker Haile bolt gun. It's favorite load is also a 165gr bullet. For 15 years that was the only hunting rifle I owned, and the 165gr Sierria Boattail and the Nosler 165gr spitzor Partition served me well. I shot everything Whitetail, Mulies, Antalope, Moose, Caribou, Hogs, Cayotes, Black Bear, even Turkey, with that gun and load. So as you can see my favorite load for .30 cal is the 165gr bullet period.