Well, I'm gonna go on record as saying that I wouldn't shoot another animal with the 168 grain Ballistic Silvertip. I shot a doe with a 308 win and it blew up, separated and made a mess. I wouldn't do it again. That bullet's not made to penetrate like the X-bullet, anyway.
Not sure if it's fair to compare the sierra to the core lockt either, especially at MAX 30-06 loads. Don't know if the poster is going to load his own 220's or use factory stuff, so I assume factory, which is slower than max.
Lets keep on track with the original post. I still feel that the faster 180 gr. X-Bullet (not a 180 Core Lockt) would out penetrate a 220 core lockt, and have more energy due to the higher velocity.
Don't forget that the gun is zeroed for the 180 Barnes, to begin with, also.