From what I've seen and read, there is no real big ballistic advantage of one over the other. The only major difference between the two, is the manufacturer, and their case designs. Plus, it only depends of what you want to have. The more cost effective route would be the Remington, of course. The Weatherbys run alittle more expensive on the ammo side, and a lot more expensive on the rifle side, on certain models. On the money-saving side, I think the Vanguards should also be offered in 7mm. Wby. According to my current catalog, a new chambering was introduced this year for them, the 257 Wby. Until they decide to do that, the Rems are the best way if you want cost effectiveness, along with good accuracy. I think Remington can/has chamber(ed) their rifles in 7mm Wby. Can anybody confirm that? If they do thats great, but the ammo still runs a few $ more. I'm not a real buff when it comes to keeping up to date on who chambers what, but others may tell a different story. In my opinion, I prefer the extra $ going to Weatherby, as with my current rifle, it has performed wonderfully. So, in my experience, I would decide on the 7mm Wby. I hope this answered your question. Patriot