Thanks to all for their input. I consider my 243 primarily an antelope gun, while the 300 WSM is for Elk, both in open country (as in Nevada open country). The gap to fill is for the Sierra Nevada and costal areas, mainly pigs, Blacktails, and some Mule Deer in the trees. It looks like a toss up, probably depending on what I can find. Has anyone loaded or shot the heavier (150 gr. +) bullets from either cartridge? I'm wondering what the practical max for the 7mm/08 is for a reloader... will it perform with the heavier (150 - 175 gr.) and round nose bullets? From what I've read the 6.5x55 will work well up to about 160 gr. (and down to about 120?), anyone have any 1st hand experience? Lastly, I'm also presuming the the recoil and muzzle blast are similar.... Thanks again !!!