I have a Vacquero in 45LC for my carry gun. With the hot load, I would not be afraid to tackle the animals mentioned out to about 75 yards. I can keep a shotgun shell size box skipping out the far pretty consistently. Beyond that, you begin having sight problems.
I have a Super Blackhawk in 44 Mag for a hunting gun if hunting. I am not afraid to shoot out past 150 with it. My loads, and my practice at silhouette allows me to go this far. Starting to get to max distance for load though.
Good luck and enjoy your choice.
Steve
