When still stalking I carry open sites, good for around fifty yards, when at my stand I scope my revolver and a shooting stick,good for 100 yards clear of sight, every individual has his own limitations, every hunter should know his own. Many days at the range and a good load for your revolver will increase your accuracy, a good hold is a good start, the way you plant your feet before shooting is another, start from the ground up even before you shoot your handgun get your stance and hold down first, practice aiming, get use to where you lock in, then start in close 20 yards until you can keep them in the ten ring, then increase your distance bye only ten to twenty feet no more, until you can do the same as the yardage you started with.
sooner than later you will find where you start loosing your accuracy. Like GBO said keep them in the pie pan, this will be your breakoff point, most of the time its around fifty yards or so using open sites and shooting a revolver standing, then you have to really practice and pay attention to every move you make when shooting out beyond 50 yards free hand, bottom line know your limitations and you will do well. Aim small hit small. RAMbo.