For intense energy transfer and deep penetration in a hollow point I have to go with Barnes XPB. On a whitetail they open completely and don't loose the mushroom petals. I have pushed them at 900 fps in 45LC and they open, upto and including 1,650 fps in my 454, they open plus they're intact. At 1,650 fps I have shot them into mud, cord wood, phone books soaked overnight with the consistancy of goop and none of it tore off any petals. On deer I base it on the entry vs the exit,(over the fps ranges listed) but more importantly it's the drastic difference of the hydraulic action in the wound channel, even soft tissue organs 6" or more away are heavily affected by the pressure. They are pricey but one definitely gets what they paid for and more. Likewise, I believe .44 mag would do very well with them.