Gentlemen,women, thank you for the input. I checked dies, sizing, chamber, and all and found everything OK. There may have been solvent (Hoppes) on the latch and popped it open I have had to check that in the past and did not check that day ( I store it in an upright rack). Pop open was a surprise, but I will be careful latching up in future. CFE223 may not be so good for 22-250 and I will go back to using H380, Varget and IMR4895. I have been getting MOA with 50 and 55 grain and want this gun to be happy. It is my best Handi shooter. Thanks.