I cast up a bunch for my .54, with a 32 twist.  The first and second firing were reasonably accurate, but they do not carry enough lube for a third loading.  If I used a grease cookie under the bullet then they had enough lube for a five shot group.  With my fast twist rifling I had to limit my loads to 80 grains of 2F or the group opened to 8 inches at 60 yards.  With 75 grains, the group size was 3 inches.  The same gun loaded with Maxi ball projectiles turns in 2.7 inch groups at 70 yards with 90 grains of 2F.  So I do not recommend the LEE REAL bullets.