I have CT grips on several guns, I have found all to be more accurate and think they provide and edge for self defense. I like the idea of being able to pull the firearm into my hip and still be able to place the shot on target; it gives me a much better field of view and allows me to concentrate on the target and the red dot while watching whats going on arond me rather than concentrating on the sights on the gun. They are especially good in low light or after dark, I wish CT offered a red/green dot with the option to switch at will to make them more effective in bright sunlight.
The guns I carry most are a Smith model 60, model 649, Kel-Tec PF-9 or a Sig 239, all will put the bullet where I place the red dot.