If you handload, the 375 Winchester does it for me! Factory ammo is almost non-existent and very expensive! However, it's perfectly capable of 300 yard shots with 200 grain bullet @ 2400+fps, or can be loaded with a 265 grain lead slug for "thinning the brush" on the way to a 100 yard shot. It will stop any critter in North America, and a few that might be on some other continents, maybe even some other planets! In a pinch, you can "blow out" a 30-30 case to use as a 375.
Like I said, it's fantanstic if you are a handloader. I've had really good luck with mine, and it's an excellent shooter capable of 1" groups if I don't flinch!
If you don't handload, then the old 30-30 can't be beat! Hard to find one that doesn't shoot well, and it's capable of taking anything on this continent as long as you keep your shots reasonable. Ammo is cheap and you can find it ANYWHERE!
If you handload, the 30-30 is capable of amazing balistics, similar to low-end 308 or 30-06 performance, expecially in the 30-30 AI. You can use factory 30-30's in the AI if your in a bind.