JMHO, I would recommend some different powder and bullets. Try Hodgdon Lil Gun and a 180gr Hornady XTP or SSPB. The H110 is a good powder too, but I think Lil Gun has the advantage.
1" accuracy at 50yds is a good place to base your loads from. You should get at least that good from a properly loaded Handi rifle in 357 Mag.
Just know that when you fire it, Spanky says it will talk to you.

Yes it will talk! It says, "max me, max me"! lol

Thanks, Dinny