At factory velocites the 22 caliber wins hands down, because while it does drop more at this power level the 22 will drift less, (less wind deflection). Pellet choice is important here, Crosman Premiers, domed, not hollow points, no pointed pellets, just plain round nosed will give the best BC value, believe me I know as I have tested them all. The same goes for the JSB, while you can shoot any pellet you want, and they will shoot, but you will probably get the best accuracy with the type of pellet mentioned, plus they hold their velocity far better.
As already mentoned, for hunting the 22 kills better at this power level
Jim