I think odds are greater that you'll encounter a two legged critter with bad intentions than a four legged one. Might even be a pack of um. Unless you're hiking in big bear country, and there's precious little of that in the 48, my choice would be the .40. I'd load it with 175-180 gr hard cast. Those will do whatever needs to be done, maybe as well as the .357. It's easy to pack a couple of extra mags In about the same space as a couple of speed loaders. That's about a 40-45rd ammo load vs 18 for the revolver and two speed loaders. I doubt that anyone ever lost a fight from having too much ammo. Now, if I were hiking in brown bear country, and couldn't carry a rifle, I'd want a big revolver, .44mag minimum.
Happy trails!
Savage