Another thought here. (I won't jump on the load as they have done a pretty good job of that already.) I will talk on the brass tho. Are you full length sizing your brass? Long straight wall brass will get what is referred to by a lot of the elder loaders as a "coke bottle effect". I have seen and measured this in my .357s, 44s, 45s, 30 carbine, etc. Cases come out of the sizing die looking kinda like ) (. This is exagerated of course.
In my FAs, I expect my new brass to have a little bit of blow by as they expand to fit the cylinder. After the initial firing, they only get sized to the depth I seat the bullet. Never any more. On brand new brass, I do a debur on the case mouth, make sure they are round, and will see if they fit in the cylinder. If they do, they will not get sized at all. Used brass is always full length sized (this is general reloading info - my FAs have never seen used brass).
Check for the "coke bottle effect" which will let the gasses by. It is especially noticable if you can see where the base of your seated bullet is in the case due to the bulge it makes in the narrow.
Good luck with your loads. Some good info posted above.
Steve
