Absolutely no problem. Been doing it for decades. I just checked the other day, Midway has a left handed safety for under twenty bucks. It takes about 10 minutes to change out. Five if you've done it a couple of times. I've never noticed the ejection either hunting or at the range over thousands of rounds. I can't say the same about my 10/22, it's always blasting stuff into my face. Good luck.
