Today's my birthday, and my daughter gave me the afternoon off.

Thank you, Sweetie.
I'm having a one man party, I'm detail cleaning my cowboy guns. While at it, I found something that has been chewed around the fires since I became been intrested in the sport.
"If you're gonna shoot black powder, you need one of the bottle neck cartridges.", or "45's have enough blow-by that they'll lock up your rifle."
Horse Feathers!!
I lucked into a '66 Uberti that seems to shoot anybodys cartridges to the same point of impact at 100'. I really enjoy this old thing and use it for almost everything, including cowboy action shooting. Now granted, I'm not one of the high volume shooters, but this rifle still goes through 1500 to 2000 rounds a year, and the only smokless that goes through it is when I take a guest shooting. The rest is all black powder.
While I had it apart, I took a good look at the bolt and the elevator, the bolt was clean as a whistle. The elevator was blacker than a coal miners....fingers, but it was just discoloration, no build up of any kind. After a good scrubbing with a stiff nylon brush and solvent, it looked the same, black but no build up. A few minutes with Brasso and the discoloration was gone. Not too bad since it's last polishing was in late winter of LAST year.
Those "OLD PROS" almost had me convinced that I was going to have to get a different rifle if I wanted to shoot black powder, but I thought I'd just give it a try before starting the search for another caliber. I'm glad I did, I like that extra 55 grains of lead! It has become my deer rifle, the one I use to dedog the farm when the drop-offs get numerous enough to pack, ground hog grinder, and down cow dispatcher.
When my "city" kids and grand kid come to visit, they always want to take it out and shoot. It makes a big boom, lots of smoke, just enough recoil to let you know that you have shot a "real" rifle, and they can usually hit what they are aiming at.
I have found that there is a "trick" to 45's and black powder that one of our more knowledgable moderators has named "a balanced load". It is really pretty simple: a case full of powder, a heavy bullet and a generous crimp. The same way it was made 130 years ago.
In summary, does a 45 have blow-by? Yes. A significant amount? Not if you go ahead and load it up the way it was designed.
So get yourself a pound of powder, some 250/255 grain bullets and add a new dimension to cowboy shooting!