I am kind of surprised that nobody has responded to this posting - let me elaborate a bit on the idea and how I arrived at the conclusion that the 405 win would be a better choice for dangerous game than the 45-70, 450 Marlin, or 444 Marlin - in an Encore pistol.
The power levels (muzzle energy) are all right at the same level, so muzzle velocities with like weight bullets are very similar, I imagine recoil too is very similar. Bullets are available from 300 grains up to 400 grains for all of the calibers listed, and well beyond for the 45 cal - although some of those bullets are designed for the big magnums and performance out of the above mentioned 45 cal cartridges may be questionable (opinion only). What makes the 405 more interesting is that their are spitzer type bullets available for it with better ballistic coefficents than the bullets availbe for the other cartridges. Less drag means the bullet will travel a longer distance before it loses enough energy to not make a clean kill, therefore with the same weight of bullet the 405 win should out-perform the others mentioned. The truth is if it wasnt for the .411 cal Barnes x spitzer bullets available for this callibur, and the Hornady brass available this project would not be near as interesting.
I admit, I don't have any ballistic software in order to simulate the 4 cartridges side by side in order to know what exactly the gain in effective range would be with the 405 win using spitzer bullets. Perhaps someone who does or has done this comparison would like to comment.
As was pointed out to me by one of the guys at handgunhunt.com the other advantage of using the 405 win is the straigt case walls and the rimmed cartridge, in a hunting situation, especially if you are truly hunting dangerous game you can just turn the barrel up and the case will just drop out so you can quickly reload (while perhaps running away)

. This won't work with a non-rimmed case, for example the 375 H&H, not sure about the 450 Marlin, but I don't think the spent cases will drop out of that one when the barrel is tipped up either - maybe someone who shoots one could comment.
