I have shot several deer with the bob, weatherby and 25/06. Generally the damage is not bad at all. The exception is with the latter two at very close range, say under 75 yards. I have noticed a bit of an increase with the faster moving bullets at close range, but even at those ranges, I still don't find it to be much of a problem. I have always been told to use a heavy for the caliber bullet if I am worried about meat loss, and I have always shot 115-120 gr bullets in the latter two.