My son has this revolver and carries it as a defense pistol.  It performs flawlessly every time he fires it, thankfully always at the range so far.  Did you buy this gun new?  I wonder if someone installed lighter main spring, or tampered with the original main spring.  I installed a Wolff spring kit in my Taurus M66 and have misfires while shooting double action using Winchester primers and am going to load some ammo using Federal primers but if I continue to have the misfires will have to reinstall the factory main spring.  Have you cleaned the action and lubed it?  How many rounds has been down the barrel?