I use both!!!!
The first gun I bought on my own was a Remington 552 Speedmaster, back in 1961...I used open sights a few years and then put a Weaver 1.5x4.5 scope on it...I killed tons of squirrels with this outfit...As far as accuracy, it's good, about 1 to 1 1/4 inch at 25 yards...But...
A few years back, I decided to treat myself to a nice .22...I bought a Remington 541-T with the curly maple stock and put a Leupold Compact
3x9x33 scope in it...With CCI Hollow Points, I can keep all shots within a dime at 50 yards...
I use them for different times of year...The Speedmaster in the early season, when they are cutting hickory nuts and acorns, most shots are well within 25 yards because you have good cover to stalk close...
The 541 in January and February, after all the leaves have fallen, where sitting is more productive than stalking...With the range of this gun, seconds shots are easy, you can reach out there and kill them, stay still, they can't stay still very long...When they don't know where you are, they don't know which way to run and I have often limited out (8 here in NC) by by never moving...