Had 2 different Fords with 302's, one a van, one a F-150. The truck I sold had 250,000 on it when I sold it, and the guy that bought it, put another 50,000 on it, before the rear end gave out. The van had 225,000 on it, and I sold it to get a one ton van, don't know how long that went before it finally gave up the ghost.
Now I'm driving a Ford E-150 with the 4.6L engine. Read and heard mixed comments on this one. It's only got a little over 50,000 on it now, switched to synthetic oil the last time I changed it. Been getting 18.9 to 19.2 mpg, holding it to 65mph. Lets see how this one holds up when I get over 200,000 on it. ('course that should happen in 2012, and my luck, the Myan curse will blow up the world, just after I get the damn thing paid for, I'll probably hit the lottery the month before too!!)