GAWI, what are you shooing, a cannon or mortar?
The reason that I ask is that if you shoot 4+ ounces in a mortar you need a heck of a lota "downrange".
I'm personally using about 3.6 ounces of 1F for blanks in my 2.25 inch mortar.
For ball (lead, about 34 ounces) I am using under 200 grains (about 170 actually) of cannon grade for 100 yard shooting.
I know 34 ounce projectiles are more than 22 ounces that the NSSA recommends, but I believe their loading table would let me use 4.5 ounces of possibly 1F (they don't really say) behind a 22 ounce ball. My charges are around 10% or less of the max recommended amount, and they are of cannon grade as well. I'm not loosing any sleep over it.
FYI, I tried an 18 ounce projectile once, and with the same 170 grain load (about the smallest that can be reliably loaded and ignited in my gun) it went well over 200 yards I think... not sure... never found it... just going by the amount of time my years told me it wa in fllgiht and pluging that into a spreadsheet I wrote.
If it was a cannon instead of a mortar I would up the charge quite a bit with projectiles. Still. I doubt I would have a need to go anywhere near the max recomended amount. I am thinking more like under 1-2 ounces of Cannon would be alot for 100-200 yard shooting.
4.5 ounces is a lot of powder behind a projectile.... not maybe from a pressure point of view, but from a muzzle energy point of view.