My M45 is over 12 years old, but it has minimum chambers unlike my Ruger in this chambering.   It is very strong, although I have not hotrodded it above the typical Ruger/TC load data.  I used it for silhouettes for years, firing a 300 LBT at 1080 fps ( just subsonic for wind drift minimization ).  Very accurate and recoil is light - not surprising with a 4# weight. Mine has the 8" barrel, a bit long for hunting but I have used it, firing a 300XTP into a Kodiak deer - one shot, one deer - but no surpise there with a proven cartridge.   :wink: