I don't know about other's experiences with 10-22s, but mine have been very positive. As far as accuracy goes, like any rifle they prefer certain ammo - I'm not saying you have to use expensive stuff either. As far as cheaper stuff goes, mine tend to like Blazer LRN 40gr. In all 6 of my 10-22s those are capable of consistent sub-1/2" 5-shot groups at 25 meters, and one of them produces 1/4" groups at 25 meters using that ammo. (These are all factory barrels with cheap scopes too, no target barrels with high-end glass.) I could probably do better with more expensive ammo but that is good enough for me to score Distinguished Rifleman at Appleseed events.
As far as cleaning goes, my 10-22s get cleaned once a year at the end of the season. They all get used at multiple high-round count events during the season since I run teen camp and family camp range days every year, and loan out my rifles for those that need them at Appleseed events, and each range day and event sees a brick of ammo or more through each rifle. I don't see more than a single malfunction out of all of the rifles during a typical season (other than failure to fire from poorly primed bulk ammo).
Likewise, my friends that have 10-22s report similar experiences, and I see a lot of other 10-22s at Appleseed events and those don't seem to have issues with malfunctions or accuracy either. I suppose some people have bad experiences with them, just like any man-made mechanical devices some are going to be better than others, and inevitably there are going to be lemons now and again. But overall they are great rifles with a well-deserved reputation for reliability and accuracy.