I am an old fan of the 357 magnum in 125 grain JHP. And no, I don't include the fraudulent 357sig. It ain't the same. I have actually USED the 357 magnum to settle an argument, and although slower than I wanted it to be, loading twice in the middle of a rather heated discussion, was stressful, but successful.
I also used a 1911 45acp to settle a disagreement, and although I prevailed in the argument, I went back to the 357 magnum THE NEXT DAY.
And so it was for almost two decades until one day the much hated (by me), Gaston Glock came out with the Glock 23 in FORTY SMITH & WESSON! The combination of the Glock 23, and the 40 S&W, for MYSELF, was the best pointing, hard hitting compromise I have ever carried or shot. The recoil from the slide cycle is easily managed, the caliber and power are right up there, and it more than doubles the round capacity of the revolver.
I will usually say that if you get into an affray with weapons it usually lasts seconds, however, I was in one that according to radio logs lasted about 13 minutes. Now I was NOT shooting all 13 minutes, but reloading was like stuffing 45 long colts in to 22 caliber chambers. I got it done, but it seemed to take forever.
The 40 S&W is my pick, in a Glock 23 or 27. It's good to go, and will come into play every bit as fast as ANY revolver.