I went with the standard 6x45mm because it's just a load and shoot where the TCU needs fireforming to befor you have brass ready to load.
Just looking at some load data for the standard 6x45mm Sierra has 70gr running at 3100fps out of a 24" barrel and Steve Timms article in Wolfe's "Wildcat Cartridges", a reprint fromm Handloader Mag. shows 3000fps for the 75gr Nosler out of a 22"barrel. I use mine as a calling rig on coyote and I'm a fur saver so I'm running 55gr NBT'ss and 55gr Blitzkings at 3350fps 22" 3 groove Pac-Nor.
AWS