Besides a .45-2.1" (AKA .45-70), I also shoot, load, & cast for a .45-2.4" (AKA .45-90) & a .45- 2 7/8 (AKA .45-110).
Don't feel that a .45-2.1" will not carry out to an extended range. It will, but you need to work around its limitations. For shooting paper/plinkin'/huntin', it will do the job.
If you are just going to reload w/ White/Nitro Powder (AKA Smokeless), it will be hard to beat a .45-2.1".
& if you are going to limit yourself to only BP, it is a most forgiving round to learn the 'how to' of reloading & casting for a BPCR.
Now for loading w/ Black powder & for extended range shooting & hunting, the .45-2.4" will have the edge. But this edge will come @ a price: more trigger time to develop an accurate load & conscientious & meticulous load development to deal w/ BP fouling & bullet alloy & lube selection.
The .45- 2 7/8 is a very fussy round to get to shoot. But once the Shooter has The Load, it will perform & perform very well indeed. Hard to beat it for long range work or a powerful hunting round, esp. w/ heavy bullet. But it will foul excessively unless the load is carefully developed.
Both the .45-2.4" 7 the .45- 2 7/8" are a step up in terms of reloading costs. The dies & brass are much more expensive & of course a pound of powder doesn't last as long when loading heavier charges.
If the Shooter is not careful w/ the selection of stock design & type of butt plate as well as a heavier barrel, the .45- 2.4" & the One-Ten will take a toll in terms of recoil. A lightweight rifle in these calibers or one w/ too much drop in the stock isn't fun to shoot. My One-Ten, a rebuilt Borchardt, weights in @ just 'bout 14 pounds & it will get tiring, esp. when shooting a 545grn bullet & a 100 grain + load.
But the crux to the weight issue is the requirements of the shooting disciplines. NRA sanctioned silhouette has a weight limit of 10 pounds, 2 oz, inc. sights; NRA BPCR Long Range, 15 pounds, inc. sights. If the Shooter wants to compete in NRA sanctioned events, the weight limits must be considered.
While it can be done, it is not wise to load White Powder in the larger cases, as the am't of space occupied by the powder is very little & it is very easy to over/double charge a hull & a wad to ensure bettrer powder ignition can lead to chamber ringing.
However, to control the fouling, increase velocity, lower the trajectory, etc. a Shooter could develop a Duplex Load ( a small White powder placed 1st in the hull, then filled w/ BP). However, a Shooter must be very careful doing so. Unless a Shooter has his/her wits 'bout him/her & has experience reloading a BPCR, I generally don't recommend such a load.
You said that you are 'newbie' to BPCR. below is a link to a thread that has links to on-line casting & reloading primers. Reloading & casting for a BPCR is not like reloading w/ White powder.
http://www.graybeardoutdoors.com/phpbb2/viewtopic.php?t=72361&sid=e712b227f8f7c1be4d47d5f0ee5eef37I also strongly urge you to visit the Shiloh-Sharps web site & do a search on the various calibers that you are interested in. There is a treasure-trove of information on that site. Esp. do a search for Kenny Wasserburger & rdnck. Both of these Shooters are very successful LR & One-Ten shooters.
http://www.shilohrifle.com/forums/index.phpThe rdnck is also the moderator of the GOEX BPCR site.
http://goexpowder.com/phpBB2/viewforum.php?f=15