So far as used to take the most game, .444 and 20 ga. ultra. Shot the most would be .444 and 45-70. I've started loading projects that will include 22 Hornet, 25-06 and 45-70. Recent trip with the 25-06 gave me 6 three shot groups that averaged 1.3 inches. Not bad but have a little more work to do. On the 45-70 I'm switching from 300gr. HP's to 350gr. RN's for a better general purpose bullets. Hopefully we'll be working on the Hornet by the end of the week.