Just my 2 cents on the subject. SSK chambers the Contender for the 375 JDJ and a number of wildcats on the 444 Marlin case which has the same case head diameter as the 250 Savage IMP, The IHMSA series of cartridges, etc. I've owned barrels for just such cartridges as has been mentioned. ANY round can be overloaded and become too much for the Contender or any other firearm, including a strong bolt action. The Contender has been chambered for rounds as large as 50 cal. , you need to know how to read pressure signs and respect that it's not as strong as some other type of actions. No reason at all a 250 AI or similar wouldn't "work" in a Contender, just not at the pressure levels it can run in a bolt action. IS that 7-250 you looked at a simple neck up or is it an improved Ackley type round ?