barrel change and the charging handle also needs changed a different actions spring can be needed, HOWEVER if you will note all makers have withdrawn all their semi auto 17's from the market. the use of a bottleneck rimfire round in a semi auto is not the worlds greatest idea, yes it can be done, yes it will work, but blowback actions make the chamber dirty quickly (not a big problem the next round just pushes the gunk out of the way with 22 cal) the bottle neck will not self clean they hang up not quiet all the way in the chamber, the 10-22 will fire from an open bold position, usually destroys the case and blows the mag out the bottom. Not really a biggie unless there is someone on your right.
Great thing about America is you have the freedom to do what you want.