I have always considered any bullet heavier than 55grs to heavy for a 1 14" twist 22-250 but then I tried some 60gr Sierra HP Varminters @ 3500fps and was amazed at the accuracy I was getting.
Shot my first wolf @ 220 yards with that bullet/cartridge combo...

I've never tried a 60gr Partition but I would definately give it a try if I felt the need, I am loading up 55gr Trophy Bonded Bear Claws so don't have the need...
