The .450 Marlin, if I remember correctly, is basically a re-worked ballistic twin to the 45-70 for lever action rifles, do-able but just to be different, IMO not worth the conversion.
The .458 Win Mag is Brutal in a Ruger, and the 45-70 can be Hot loaded to within 300 fps of the Maggie (in a Ruger) both of which are a bit much for the SB2 frame.
The .450 BP express (instead of the .450 #2 Nitro) is likely to be the best bet but the express Rifles all push 300 to 500 grain bullets to around 2,100 to 2,800 fps (in original rifles, depending on barrel regulation)
The .45-90, 45-110, .45-120 etc can be interesting, but the price of brass for these is around $2.00 each. Each (even the 45-70) can be loaded too hot for the Handi to handle)
Just my 2 cents