Strange timing on this subject because I went though a similar thought process last night at bedtime.  My deer rifles run from 243,  25-06, 270, 7-30, 7mm-08, 280, 280Ack, 7mm mag, 30-06, 308, and 300 WSM.  I was getting the itch for another rifle when I realized my plain vanilla 270 ADL is a sweet shooting rifle, easy to load for, and does everything I want from any of the other rifles.  Additionally, it has a zero collectors value so i do not have to be so particular with it in the truck or field.  It's just a gun, not a show piece.  The scope is worth more than the rifle, yet it is a proven workhorse.
 
Wouldn't be any fun to downsize to the 270 only but certainly it would do all I ever need on North America.