I have actually shot a deer with my 4095, and it will get the job done. Results were not spectacular, in fact the deer didn't show any sign of being hit, she just wheeled and ran away. The distance was about 25 yards with Hornady 180 xtp's, it was a double lung broadside shot, and the bullet came to rest under the skin on the off side, breaking one rib going in and one going out. Blood trail was light and the doe went @75 yrds. I don't know if the 45 ACP would have done any better, dead is dead, a hard cast bullet may have provided a complete pass thru and a better blood trail. anyway a 45 ACP Carbine is in my future and I will shoot a deer with it or at least a hog and will post how it does.