I have used both, and also look forward to using the excellent Lyman Devastator Hp.  I have pretty much settled on thre bullets for all my self defense/ hunting needs.  Primarily, the Devastator.  I penetrates enough in testing, is very accurate, and makews a hole you wouldn't believe. Second, a 250 grain Keith.  Ditto, except the 250 is non gas check..  I use it a lot for self defense training.  third the lee 310 grain flat point.  very accurate, massive penetrationand damage.  These three are pretty much interchangable, although i wouldn't want to use the 310 grain in a gun battle around bystanders, in a pinch, it would put a bad guy DOWN.