I know a guy that helped develop the 500 S&W brass... only use rifle primers and expect a lot of pain if you ever max those cases out. the brass is built to stand way more psi than is actually sensible to generate.. your body will hurt and your gun will wear out quick if you screw up.. do not use max loads. max loads are about 60,000 psi. it's advisable to stay under 50,000psi to avoid loosening primer pockets, squishing the heads, and drastically reducing case life. it's thick brass but just the same as the rest on a molecular level- it can only take so much stress. also remember that such heavy bullets backed by slow powders will "push" you more than hit you, it'll move you a bit (same force but more follow-through)
use protection for your face, and your dominant hand, and check the brass after you fire.. I read that you do not handload. at least take the time to thoroughly study case-life and stress features. if you don't like the maximum power offered, please consifer handloading. handloading will offer you anything from 200ish to 700grs bullets and any speed you want under 2k is attainable with the light to mid weight bullets.