I am not using a 454 Casull, but a Smith & Wesson 500 and a BFR is S&W500 and I have red dots on them. I have a Bushnell Holo sight on my Smith & Wesson 500 with over 200 rounds of 440 gr. full loads. Not one problem. I have an Ultra Dot on my BFR in S&W500 and have well over 300 rounds of full load 440 gr. rounds through it. Again not one problem. I had a Millet on my Super Ruger Redhawk and blew it out after 10 rounds, but got it replaced from Millet and it is still holding up. I don't know about the c-more railway sight. If it does not work try one of the ones I listed above, they worked for me. As far as Tasco I have a Pro Point on my Redhawk in 44MAG and have well over 1500 rounds through it and have had not problems. Also consider Aim Point.