Well, let's see now....I've taken about 15 or so critters with the 300 gr. nosler partition, albeit in a Marlin .45-70 GG. I started out using the Win. Supreme factory load, and when I wasn't able to get any more, I started handloading it with H4198. Penetration is awesome! I have sot end to end thru several critters. I took the load and gun to south africa last year, for my plains game safari. I shot 7 animals with it, and the bullet performed flawlessly. Size wise, the upper end animals were 450-700+ lbs. Here are some pics of the biggest critters, and 1 pic of the ONLY recovered noslers I have ever gotten.

kudu, about the size of avg. bull elk.

blue wildebeast

zebra. probably the toughest animal I have ever shot.

gemsbok. one tough hombre!

the only noslers I have ever recovered. all the rest were passthroughs. For my money, the 300 gr. nosler partition is one of the best bullets you can use on game, other than big/dangerous game.
Mad Dog